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Top Nike Running Shoes for Knee Pain Relief in 2025

BY POIZON / UPDATED: 2025-06-06 13:52:02

If you're struggling with knee pain while running, finding the right pair of shoes is crucial. Nike offers a range of running shoes specifically designed to provide comfort and support, helping to alleviate discomfort during your workouts. From the lightweight Nike ZoomX Invincible Run 3 to the cushioned Nike Air Zoom Pegasus 40, each shoe is crafted with advanced technology to ensure a smooth running experience. Whether you're a beginner or looking for something more advanced, POIZON has you covered with a curated selection of Nike running shoes that cater to your needs. Explore the options below to find the perfect fit for your running journey!

Nike

Nike ZoomX Invincible Run 3 Bright Crimson

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The Nike ZoomX Invincible Run 3 in Bright Crimson is designed for beginner runners seeking comfort and support. Weighing approximately 270g, this low-top shoe features a slip-resistant and abrasion-resistant upper made from polyester. Ideal for various surfaces, including treadmills and highways, it offers a round toe style and a flat heel for stability. The shoe's design is perfect for casual training in any season, making it a versatile choice for those looking to alleviate knee pain while enjoying their runs.

Pros:

Lightweight design

Slip-resistant functionality

Versatile for multiple surfaces

Stylish color scheme

Nike

Nike Air Max Scorpion Mid Top Air Cushion Running Shoes Unisex White

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The Nike Air Max Scorpion Mid Top Air Cushion Running Shoes are perfect for those who prioritize comfort and support. With a mid-top design and air cushion sole technology, these shoes provide excellent shock absorption, making them ideal for individuals with knee pain. The fabric upper ensures breathability, while the lace-up closure offers a secure fit. Suitable for casual wear and various surfaces, these shoes are a great addition to any runner's collection.

Pros:

Air cushion technology for comfort

Breathable fabric upper

Secure lace-up closure

Stylish mid-top design

Nike

Nike Air Zoom Pegasus 38 Black White

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The Nike Air Zoom Pegasus 38 in Black and White is a reliable choice for beginner runners. Weighing around 280g, this low-top shoe features Nike's Air Zoom and React sole technology, providing excellent cushioning and support for those with knee pain. The slip-resistant design ensures safety on various surfaces, making it suitable for both casual and training scenarios. Its classic color scheme adds a touch of style to your running gear.

Pros:

Excellent cushioning

Slip-resistant design

Versatile for training

Classic color scheme

Nike

Nike Air Zoom Pegasus 39 Shield Triple Black Women's

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The Nike Air Zoom Pegasus 39 Shield in Triple Black is designed for those who want a stylish yet functional running shoe. Weighing approximately 282g, this low-top shoe features a slip-resistant design and is suitable for various surfaces. Its sleek black color scheme makes it a fashionable choice for casual outings as well. The shoe's cushioning technology helps alleviate knee pain, making it a great option for beginner runners.

Pros:

Stylish design

Good cushioning

Slip-resistant

Versatile for casual wear

Nike

Nike Air Zoom Winflo 10 'White Black Crimson'

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The Nike Air Zoom Winflo 10 in 'White Black Crimson' is a lightweight running shoe weighing about 265g. This low-top shoe features a slip-resistant design, making it suitable for various surfaces. Its stylish color scheme and comfortable fit make it a great choice for casual runners looking to ease knee pain while enjoying their runs. The shoe's design ensures stability and support, making it a reliable option for beginners.

Pros:

Lightweight design

Stylish color scheme

Slip-resistant functionality

Good for casual running

Nike

Nike Air Zoom Pegasus 40 White Deep Royal Blue

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The Nike Air Zoom Pegasus 40 in White and Deep Royal Blue is a fantastic option for beginner runners. Weighing approximately 290g, this low-top shoe features Nike React technology for excellent shock absorption, which is crucial for those with knee pain. The slip-resistant design ensures safety on various surfaces, making it suitable for both casual and training scenarios. Its stylish color scheme adds a modern touch to your running gear.

Pros:

Great shock absorption

Stylish design

Slip-resistant

Versatile for training

Nike

Nike Revolution 6 Next Nature Black White

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The Nike Revolution 6 Next Nature in Black and White is a lightweight running shoe weighing around 256.9g. This low-top shoe features a breathable upper and slip-resistant design, making it suitable for various surfaces. Its shock-absorbing technology helps alleviate knee pain, making it a great choice for casual runners. The stylish color scheme ensures you look good while staying comfortable during your runs.

Pros:

Lightweight and breathable

Shock-absorbing technology

Stylish color scheme

Slip-resistant

Nike

Nike Air Zoom Alphafly Next% 3 Volt Concord

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The Nike Air Zoom Alphafly Next% 3 in Volt Concord is an advanced running shoe designed for serious runners. Weighing only 223g, this low-top shoe features a carbon plate for enhanced propulsion and a slip-resistant design. While it is more suited for marathon runners, its lightweight and supportive design can also benefit those with knee pain looking for a high-performance option.

Pros:

Lightweight and responsive

Advanced propulsion technology

Slip-resistant

Stylish design

Nike

Nike Wearallday White Black

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The Nike Wearallday in White and Black is a versatile running shoe weighing approximately 290g. This low-top shoe features a slip-resistant design, making it suitable for various surfaces. Its stylish color scheme and comfortable fit make it a great choice for casual runners looking to ease knee pain while enjoying their runs. The shoe's design ensures stability and support, making it a reliable option for beginners.

Pros:

Versatile for casual wear

Stylish design

Slip-resistant

Comfortable fit

Nike

Nike Air Zoom Pegasus 39 Shield 'Black Dark Smoke Grey'

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The Nike Air Zoom Pegasus 39 Shield in 'Black Dark Smoke Grey' is designed for those who want a stylish yet functional running shoe. Weighing approximately 260g, this low-top shoe features a slip-resistant design and is suitable for various surfaces. Its sleek black color scheme makes it a fashionable choice for casual outings as well. The shoe's cushioning technology helps alleviate knee pain, making it a great option for beginner runners.

Pros:

Stylish design

Good cushioning

Slip-resistant

Versatile for casual wear

With POIZON's commitment to authenticity and quality, you can shop with confidence knowing that each pair of shoes has been thoroughly vetted. Elevate your running experience and take the first step towards pain-free workouts with the right footwear. Don't let knee pain hold you back; invest in a pair of Nike running shoes today!

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